On the 17th of November last year 
Stephen C. Meyer delivered a lecture at the 
Royal Horseguards Hotel in London, at an event sponsored by the 
Centre for Intelligent Design. The lecture, hosted by 
Lord Mackay of Clashfern, was titled "Is there a Signature in the Cell?" — presumably based on Meyer's similarly titled book, 
Signature in the Cell. The three Pauls talked about the lecture 
on our Skepticule Extra podcast, but I thought it might be useful to put my own thoughts on it in writing (though much of this will be a repeat of what I said on on the podcast).
The event was shrouded in a certain amount of spurious secrecy, as can be seen from 
this extract from the C4ID website:
The audience of some 90 invited guests included leading scientists,  philosophers, Parliamentarians, educationalists, theologians, lawyers,  and representatives of the media and business sectors.  Given the  controversial nature of the subject and the desire not to inhibit  discussion, C4ID requested that the identity of the participants remain  protected.  The attendance of so many significant figures signals real  interest in the topic, but, as Lord Mackay stressed in his introduction,  their presence was not taken as an indication of support for the  position of Intelligent Design (ID)
 
Also in the audience was 
Justin Brierley, host of Premier's 
Unbelievable? radio programme, who 
posted this on Facebook:

 
I have a confession... I'm coming off the fence over ID, well certainly at least with the origin of DNA. This lecture which I attended recently and the shows I have done convince me that when it comes to biogenesis, ID makes sense. 
I've been criticised by theistic evolutionists for featuring ID on the show. But when it comes down to it, I don't see the difference. If TE says that the process that kick started evolution was in some sense goal oriented by divine guidance - then isn't that the same as saying that the assembly of the first self replication molecule was not down to blind forces and chance? Which is essentially what Stephen Meyer argues.
Some Christian don't like the theological implications of God "tinkering" but if we believe God intervenes in all kinds of other ways in miracles, the resurrecion etc. why shoudn't the moment of life's creation fall under this? And if the problem is that it doesn't look good theologically, then aren't the TEs doing what they critices YECs for - allowing their theological presuppositions to dictate what is allowed in the scientific realm.
I dont have a theological axe to grind when it comes to ID, I just think that given what we know now, and because I can't see good reason why deisgn isn't a viable explanation, it is the best explanation.
Just my musings, feel free to tear them apart!
 
Some months after the lecture a video of it was 
made available on YouTube, so I decided to watch it. What follows are some thoughts triggered as I watched.
http://youtu.be/NbluTDb1Nfs
Meyer begins with some sensible localisation, stating that in the United States 
Intelligent Design is perceived as connected  to 
Young Earth Creationism. This is not so in the United Kingdom — because in the UK we never had the equivalent of the Scopes trial. This is presumably because in the UK we don't have separation of Church and State (even though we might be viewed as a more secular society than the US).
Meyer goes on to make a number of general points, beginning with the main point of ID, the Question of Design — is there a  mind behind biological complexity? He mentions 
Richard Dawkins, oddly suggesting that he's not regarded as seriously  as he used to be, due to his media involvement. This might be wishful thinking on Meyer's part, but nevertheless Meyer says he likes Dawkins'  directness.
Meyer then claims that 
"today  there is a very spirited discussion going on about the adequacy of  natural selection and random mutation to produce not the minor  variations … but the fundamental innovations in the history of  life." He doesn't cite any sources for these spirited discussions, which makes me think this is merely sowing the seeds of doubt, as he's clearly doing when he claims that many evolutionary  biologists are now saying that neo-Darwinian mechanics of mutation  and selection are insufficient to produce large scale innovations. Again no direct sources — how many is 'many'? And the introduction of "large scale innovations" hints that he's favouring "micro-evolution" over "macro-evolution".
The origin of life — of the first  cell — is not explained by Darwinian evolution, Meyer says, which appears to be an effort on his part to bias the story. He's asking how can Darwin be said to have refuted the design argument if he was unable to explain the "design" of the first cell. As far as I'm aware that's not what happened; Darwin showed that a  designer was not necessary for evolution, but admitted ignorance of  the origin of life. ID proponents such as Meyer are spinning this as a  disingenuous claim by evolutionists, when it's nothing of the kind.
Meyer says the acceptance of  ignorance about the origin of the first cell is due to a prevailing  view that life was 
simple — a globule of plasm — and the  intellectual leap to evolving life wasn't that great. Then we're on to some particular buzzwords beloved by the ID crowd, beginning with "sequence specificity". Something is  "sequence specific" if the 
sequence determines the  form (and therefore the function). Meyer shows an animation to illustrate  how proteins are synthesized — starting with the sequence of genes  along the spine of a DNA molecule. It all looks very complicated, but presumably illustrates how  
present-day cells work. It's likely, it seems to me, that the very first self-replicating cells were far simpler.
The "DNA Enigma", Meyer claims, concerns the origin of information, and he explains that there are two* types of information: 
Shannon information — the reduction   of uncertainty, by which the more improbable an event, the    more information is conveyed by the outcome of that event (in a    strictly mathematical sense), but this cannot account for 'specified'    complexity. He seems to be saying that specified complexity is present if you recognize what a given    sequence represents. That, it seems to me, is 
post hoc rationalisation, as if "specified  complexity" refers to complexity that contains information that  has no apparent correlation to the function it produces —  suspiciously like an argument from ignorance — and yet can only be recognised after the fact. As usual with ID proponents, this claim to be able to identify design isn't elaborated before we're on to something else — in this case a quotation from 
Jacques Monod: "A striking appearance of  design." Monod apparently attributes this striking appearance to chance or necessity, or a  combination of the two, in explaining natural processes.
Meyer says chance can produce the "appearance of design", but it's only good for short   sequences. But what about selection? Meyer claims that applying   natural selection to the origin of life is begging the question —   invoking replication and 'life' in order to explain life's origin. I think, however, that he may be too restrictive in his ordering — natural   selection doesn't have to kick in only after DNA, it can presumably   operate on the simplest self-replicating molecules — the very   first precursors to DNA/RNA etc.
Meyer goes on to mention the RNA  world (which approximates to what I suggested above). He says the  RNA world is problematic and he's happy to speak about it in the  Q&A and that he covers it in his book. This, to me, seems like a cop-out.
Monod's third option is 
 self-organisation. But chemistry alone, Meyer says, cannot determine the sequence  of bases in DNA. So we don't know what determines the  base sequence — once again we're back to an argument from  ignorance. He says it's not the physics  and chemistry that determines the sequence — when what he probably means is  that he can't think of any mechanism by which physics and chemistry  could determine the sequence.
Meyer then invokes an "inference to the best  explanation", but unfortunately what he proposes isn't actually  an explanation. It offers nothing extra, over and above what "I  don't know" offers. The reason why we can make inferences to  the best explanation in other areas — why we can speculate about  possible 
causes for events or phenomena, is we understand how  those causes work. It's no good proposing a cause when we don't know  how that cause works, because that doesn't have any explanatory  power. "It was designed" doesn't explain anything unless  we can say 
how it was designed. This is my fundamental  objection to ID.
By way of example of such an inference Meyer uses the presence of  geological layers of volcanic ash. That's a valid example, because we know how  volcanoes produce layers of volcanic ash. It's 
not valid for  inferring a design to first life.
Meyer concludes with a lame graphic  to illustrate the argument he uses in his book, 
Signature in the  Cell. He has four options to explain the appearance of design: 1) Chance; 2) Necessity; 3) Chance 
plus Necessity; 4) ID — and then he eliminates all  but ID. But he's not established that these are the only  options, and they could 
all be wrong.
The video then jumps to the Q&A session, but apparently only the final question. The screen indicates Meyer might have been discussing the accusation that ID is an argument from ignorance, but from what's actually on the screen I don't think he could have done it very well, as the graphics seemed to reinforce the idea that ID is indeed an argument from ignorance.
The final question was "What is Science?" Meyer says it's a method, and mentions that this is relevant to whether ID is or is not science. But he says he's not interested in whether ID is science, only in whether it's true (or more likely to be true). He claims that the accusation that ID is not science is a ploy to avoid discussing it scientifically. I could just as easily say that his lack of concern about whether ID is science is a ploy to avoid applying the scientific method to it. He claims throughout his lecture, however, that he's using the kind of science employed by Charles Darwin.
A 
URL at the end of the video invites people to download a 
free digital companion to the book. I did this, even though I had to register with the 
Discovery Institute in order to get the 
PDF, though I've not yet read it. It appears to be a response to various criticisms of 
Signature in the Cell.
Most apparent from this lecture is that despite a resurgence of interest in the UK (manifested by the formation of 
C4ID in Scotland), ID has nothing new to offer on the question of life's origins, and remains hidebound in a tacit endorsement of scriptural infallibility. ID is an explanation of sorts, if you have fairly low expectations of what an "explanation" is supposed to tell you, but isn't in any sense a 
scientific explanation.
As far as I recall, Meyer didn't elucidate the second type.